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Beyond the "selfish mitochondrion" theory of uniparental inheritance: A unified theory based on mutational variance redistribution.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 May 2021

Radzvilavicius Arunas

Abstract excerpt

"Selfish" gene theories have offered invaluable insight into eukaryotic genome evolution, but they can also be misleading. The "selfish mitochondrion" hypothesis, developed in the 90s explained uniparental organelle inheritance as a mechanism of conflict resolution, improving cooperation between genetically distinct compartments of the cell. But modern population genetic models provided a more general explanation...

Topics

Eukaryota
Genome
Heredity
Mitochondria
Mutation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33729620
DOI: 10.1002/bies.202100009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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