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Article

Selective sweeps of mitochondrial DNA can drive the evolution of uniparental inheritance.

Evolution; international journal of organic evolution - 1 Aug 2017

Christie Joshua R, Beekman Madeleine

Abstract excerpt

Although the uniparental (or maternal) inheritance of mitochondrial DNA (mtDNA) is widespread, the reasons for its evolution remain unclear. Two main hypotheses have been proposed: selection against individuals containing different mtDNAs (heteroplasmy) and selection against "selfish" mtDNA mutations. Recently, uniparental inheritance was shown to promote adaptive evolution in mtDNA, potentially providing a third...

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PMID: 28640391
DOI: 10.1111/evo.13291

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