Two Infection Assays to Study Non-Lethal Virulence Phenotypes in C. Albicans using C. Elegans.

Abstract excerpt

While pathogens can be deadly to humans, many of them cause a range of infection types with non-lethal phenotypes. Candida albicans, an opportunistic fungal pathogen of humans, is the fourth most common cause of nosocomial infections which results in ~40% mortality. However, other C. albicans infections are less severe and rarely lethal and include vulvovaginal candidiasis, impacting ~75% of women, as well as...

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• Caenorhabditis elegans
• Candida albicans
• Candidiasis
• Disease Models, Animal
• Mice