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Candida albicans Hyphal Formation and Virulence Assessed Using a Caenorhabditis elegans Infection Model

7 Aug 2009

Abstract excerpt

Candida albicans colonizes the human gastrointestinal tract and can cause life-threatening systemic infection in susceptible hosts. We study here C. albicans virulence determinants using the nematode Caenorhabditis elegans in a pathogenesis system that models candidiasis. The yeast form of C. albicans is ingested into the C. elegans digestive tract. In liquid media, the yeast cells then undergo morphological...

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PMID: 19666778
DOI: 10.1128/ec.00163-09

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