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Article

Metabolic Traits and Stroke Risk in Individuals of African Ancestry: Mendelian Randomization Analysis.

Stroke - 1 Aug 2021

Fatumo Segun, Karhunen Ville, Chikowore Tinashe, Sounkou Toure, Udosen Brenda, Ezenwa Chisom, Nakabuye Mariam, Soremekun Opeyemi, Daghlas Iyas, Ryan David K, Taylor Amybel, Mason Amy M, Damrauer Scott M, Vujkovic Marijana, Keene Keith L, Fornage Myriam, Järvelin Marjo-Riitta, Burgess Stephen, Gill Dipender

Abstract excerpt

BACKGROUND AND PURPOSE: Metabolic traits affect ischemic stroke (IS) risk, but the degree to which this varies across different ethnic ancestries is not known. Our aim was to apply Mendelian randomization to investigate the causal effects of type 2 diabetes (T2D) liability and lipid traits on IS risk in African ancestry individuals, and to compare them to estimates obtained in European ancestry individuals....

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Identifiers

PMID: 34078102
DOI: 10.1161/STROKEAHA.121.034747
PMCID: PMC8312569

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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