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Article

Computational analysis of the effect of KCNH2 L532P mutation on ventricular electromechanical behaviors.

Journal of electrocardiology - 1 Jan 2000

Heikhmakhtiar Aulia Khamas, Dusturia Nida, Lim Ki Moo

Abstract excerpt

The KCNH2 L532P mutation is an alteration in the IKr channel that is associated with short QT syndrome and atrial fibrillation in zebrafish. In preliminary studies, the electrophysiological effects of the hERG L532P mutation were investigated using a mathematical model in a single-cell and 2D sheet medium. The objective of this study was to quantify the effects of the KCNH2 L532P mutation on the 3D ventricular...

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Identifiers

PMID: 33721574
DOI: 10.1016/j.jelectrocard.2021.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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