Article
GWAS findings improved genomic prediction accuracy of lipid profile traits: Tehran Cardiometabolic Genetic Study.
Scientific reports - 11 Mar 2021
Akbarzadeh Mahdi, Dehkordi Saeid Rasekhi, Roudbar Mahmoud Amiri, Sargolzaei Mehdi, Guity Kamran, Sedaghati-Khayat Bahareh, Riahi Parisa, Azizi Fereidoun, Daneshpour Maryam S
Abstract excerpt
In recent decades, ongoing GWAS findings discovered novel therapeutic modifications such as whole-genome risk prediction in particular. Here, we proposed a method based on integrating the traditional genomic best linear unbiased prediction (gBLUP) approach with GWAS information to boost genetic prediction accuracy and gene-based heritability estimation. This study was conducted in the framework of the Tehran...
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