Article
Characteristics and diversity of mutations in regulatory genes of resistance-nodulation-cell division efflux pumps in association with drug-resistant clinical isolates of Acinetobacter baumannii.
Antimicrobial resistance and infection control - 10 Mar 2021
Salehi Bahare, Ghalavand Zohreh, Yadegar Abbas, Eslami Gita
Abstract excerpt
BACKGROUND: This study was aimed to characterize the genetic diversity and expression of three putative resistance-nodulation-cell division (RND)-type efflux systems and their contribution to multidrug efflux in clinical isolates of Acinetobacter baumannii. METHODS: Antimicrobial susceptibility testing of 95 A. baumannii isolates was determined by Kirby-Bauer disk diffusion for 18 antibiotics and minimum...
Topics
- Acinetobacter baumannii
- Aged
- Bacterial Proteins
- Cell Division
- Drug Resistance, Multiple, Bacterial
- Gene Expression Regulation, Bacterial
- Genes, Regulator
- Humans
- Iran
- Male