Effect of Spermidine on Biofilm Formation in Escherichia coli K-12.

Abstract excerpt

Polyamines are essential for biofilm formation in Escherichia coli, but it is still unclear which polyamines are primarily responsible for this phenomenon. To address this issue, we constructed a series of E. coli K-12 strains with mutations in genes required for the synthesis and metabolism of polyamines. Disruption of the spermidine synthase gene (speE) caused a severe defect in biofilm formation. This defect...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Culture Media
• Share to Acetyltransferases
• Share to Biofilms