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Article

A self-produced trigger for biofilm disassembly that targets exopolysaccharide.

Cell - 27 Apr 2012

Kolodkin-Gal Ilana, Cao Shugeng, Chai Liraz, Böttcher Thomas, Kolter Roberto, Clardy Jon, Losick Richard

Abstract excerpt

Biofilms are structured communities of bacteria that are held together by an extracellular matrix consisting of protein and exopolysaccharide. Biofilms often have a limited lifespan, disassembling as nutrients become exhausted and waste products accumulate. D-amino acids were previously identified as a self-produced factor that mediates biofilm disassembly by causing the release of the protein component of the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 22541437
DOI: 10.1016/j.cell.2012.02.055
PMCID: PMC3526955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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