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Spermidine facilitates the adhesion and subsequent invasion of <i>Salmonella</i> Typhimurium into epithelial cells via the regulation of surface adhesive structures and the SPI-1

2023-06-03

Abstract excerpt

Polyamines are poly-cationic molecules ubiquitously present in all organisms. Salmonella synthesizes and also harbors specialized ABC transporters to uptake polyamines. Polyamines assist in pathogenesis and stress resistance in Salmonella ; however, the mechanism remains elusive. The virulence trait of Salmonella depends on the injection of effector proteins into the host cell and modulation of host machinery a...

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Literature Corpus work
02cff1ad-fac2-5392-b517-721ee0181aa0
DOI
10.1101/2023.06.03.543567
Open publication

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