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Article

Molecular Profiling and Targeted Therapy in Cholangiocarcinoma: An Observational, Retrospective Multicenter Study.

Journal of gastrointestinal cancer - 1 Jun 2021

Garcia-Pardo Miguel, Ortega Laura, Fernández-Aceñero María Jesús, García Alfonso Pilar, Martín Miguel, Muñoz Andrés J

Abstract excerpt

PURPOSE: Cholangiocarcinoma (CCA) is an aggressive biliary tract malignancy and overall prognosis remains poor, with a median survival of less than 24 months. Sequencing studies have revealed a high prevalence of genomic alterations in CCA, with multiple potential therapeutic targets. Next-generation sequencing (NGS) can identify actionable mutations such as FGFR, IDH, BRAF, ERBB2, ROS1, or microsatellite...

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Identifiers

PMID: 33683644
DOI: 10.1007/s12029-021-00622-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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