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OBSCN as biomarker for evaluating tumor mutation burden and anti-tumor immunity in Stomach adenocarcinoma

2022-04-25

Abstract excerpt

<h4>Background: </h4> Somatic mutations are strongly linked to cancer. Tumor mutation burden (TMB), PD-L1, and CTLA-4 are considered to be important biomarkers for selecting patients with stomach adenocarcinoma (STAD) for immune checkpoint inhibitors (ICIs) therapy. Nonetheless, whether specific gene mutations are related to prognosis, TMB, sensitivity to ICIs, and tumor-infiltrating immune cells remains unclear....

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Literature Corpus work
9d93b3e9-4292-539b-a0c1-1a0637e35dd7
DOI
10.21203/rs.3.rs-1582774/v1
Open publication

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OBSCN as biomarker for evaluating tumor mutation burden and anti-tumor immunity in Stomach adenocarcinomaDOI 10.21203/rs.3.rs-1582774/v1
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