Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of Genomic Instability-Related Molecules: Cyclin F, RRM2 and SPDL1 and Their Prognostic Significance in Pancreatic Adenocarcinoma

18 Feb 2021

Abstract excerpt

In the present study, we aimed to assess the selected components of cell cycle machinery, checkpoint, DNA repair, and synthesis, namely RRM2, cyclin F, and SPDL1 in pancreatic adenocarcinomas (PAC) by in-house immunohistochemistry (IHC) and bioinformatic analysis of public datasets, in terms of expression, correlation with clinicopathological parameters, and patient survival. Sixty eight patients with pancreatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Pancreatic and Hepatic Oncology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33670609
DOI: 10.3390/cancers13040859

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of Genomic Instability-Related Molecules: Cyclin F, RRM2 and SPDL1 and Their Prognostic Significance in Pancreatic AdenocarcinomaPMID 33670609Read ↗

Immunohistochemically detected expression of 3 major genes (CDKN2A/p16, TP53, and SMAD4/DPC4) strongly predicts survival in patients with resectable pancreatic cancer.Semantic proximity Read ↗

Characterization of the genomic landscape in large-scale Chinese patients with pancreatic cancer.Semantic proximity Read ↗

Curation of the Pancreatic Ductal Adenocarcinoma Subset of the Cancer Genome Atlas Is Essential for Accurate Conclusions about Survival-Related Molecular MechanismsSemantic proximity Read ↗

Genome‐wide array‐based comparative genomic hybridization analysis of pancreatic adenocarcinoma: Identification of genetic indicators that predict patient outcomeSemantic proximity Read ↗

Hypermethylated CACNB2 Predicts Poor Prognosis And Promotes Proliferation, Invasion and Apoptotic Resistance in Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Drivers of Gene Expression Dysregulation in Pancreatic Cancer.Semantic proximity Read ↗

Prognostic relevance of molecular subtypes and master regulators in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Genomic analyses identify biological processes of pancreatic cancer after radiotherapySemantic proximity Read ↗

Integration of Bioinformatics Resources Reveals the Therapeutic Benefits of Gemcitabine and Cell Cycle Intervention in SMAD4-Deleted Pancreatic Ductal AdenocarcinomaSemantic proximity Read ↗

Integrative Survival-Based Molecular Profiling of Human Pancreatic CancerSemantic proximity Read ↗

Targeting DNA Damage Response and Replication Stress in Pancreatic CancerSemantic proximity Read ↗

Comprehensive Bioinformatics Analyses and Experimental Validation of the Cell Cycle Related Protein SAPCD2 as a New Biomarker and Potential Therapeutic Target in Pancreatic CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.