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Article

Integrative Survival-Based Molecular Profiling of Human Pancreatic Cancer

19 Jan 2012

Abstract excerpt

PURPOSE: To carry out an integrative profile of human pancreatic ductal adenocarcinoma (PDAC) to identify prognosis-significant genes and their related pathways. EXPERIMENTAL DESIGN: A concordant survival-based whole genome in silico array analysis of DNA copy number, and mRNA and miRNA expression in 25 early-stage PDAC was carried out. A novel composite score simultaneously integrated gene expression with...

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PMID: 22261810
DOI: 10.1158/1078-0432.ccr-11-1539

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