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The HLA-DR4-DQ8 phenotype of the recipient is associated with increased mortality after kidney transplantation.

Clinical immunology (Orlando, Fla.) - 1 May 2021

Lund Kit P, Eriksson Frank, Hauge Anne W, Mora-Jensen Helena I, Sørensen Søren S, Bruunsgaard Helle

Abstract excerpt

The importance of the human leukocyte antigen (HLA) system in kidney transplantation is well-known, but it remains unexplored if patient HLA antigens constitute independent risk factors in complications after transplantation. We hypothesized that specific HLA class II phenotypes associated with immune-mediated disease (HLA-IMD) predispose to immunological activity and/or complications after kidney...

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Identifiers

PMID: 33667637
DOI: 10.1016/j.clim.2021.108711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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