Article
DIG-1, a novel giant protein, non-autonomously mediates maintenance of nervous system architecture.
Development (Cambridge, England) - 1 Sept 2006
Bénard Claire Y, Boyanov Alexander, Hall David H, Hobert Oliver
Abstract excerpt
Dedicated mechanisms exist to maintain the architecture of an animal's nervous system after development is completed. To date, three immunoglobulin superfamily members have been implicated in this process in the nematode Caenorhabditis elegans: the secreted two-Ig domain protein ZIG-4, the FGF receptor EGL-15 and the L1-like SAX-7 protein. These proteins provide crucial information for neuronal structures, such...
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