Article
Intragenic Variations in BTLA Gene Influence mRNA Expression of BTLA Gene in Chronic Lymphocytic Leukemia Patients and Confer Susceptibility to Chronic Lymphocytic Leukemia.
Archivum immunologiae et therapiae experimentalis - 1 Dec 2016
Karabon Lidia, Partyka Anna, Jasek Monika, Lech-Maranda Ewa, Grzybowska-Izydorczyk Olga, Bojarska-Junak Agnieszka, Pawlak-Adamska Edyta, Tomkiewicz Anna, Robak Tadeusz, Rolinski Jacek, Frydecka Irena
Abstract excerpt
The aim of this study was to determine the association between polymorphisms in gene encoding B- and T-lymphocyte attenuator (BTLA) and susceptibility to chronic lymphocytic leukemia (CLL) and their influence on mRNA expression of BTLA gene in T and B cells from CLL patients (pts.). The following BTLA single-nucleotide polymorphisms (SNPs): rs2705511, rs1982809, rs9288952, rs76844316, rs16859633, ,...