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Article

Association of BTLA rs1982809 polymorphism with lung cancer risk in Tunisian population.

International journal of immunogenetics - 1 Dec 2020

Khadhraoui Chaima, Kaabachi Wajih, Tritar Fatma, Daghfous Hafaoua, Hamzaoui Kamel, Hamzaoui Agnes

Abstract excerpt

B and T lymphocyte attenuator (BTLA) is an immune-inhibitory receptor that negatively regulates the lymphocyte activation. A few studies have been devoted to the relationship between BTLA gene variations and cancer's risk. It has been essentially demonstrated to be involved in increasing cancer risk in chronic lymphocyte leukaemia, renal cell carcinoma, breast and colorectal cancer predispositions in Asian...

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PMID: 32757486
DOI: 10.1111/iji.12491

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