Article
Association of a BTLA gene polymorphism with the risk of rheumatoid arthritis.
Journal of biomedical science - 1 Nov 2006
Lin Shih-Chang, Kuo Chia-Chen, Chan Chia-Hsi
Abstract excerpt
B and T lymphocyte attenuator (BTLA) is an immuno-inhibitory receptor with the ability to deliver inhibitory signal for suppressing lymphocyte activation. To test the potential association of the human BTLA gene with the development of rheumatoid arthritis (RA), a genetic case-control association study was conducted, by using a single nucleotide polymorphism (SNP), C+800T SNP, in the exon 5 of the human BTLA gene...
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