Article
Association of 3' nearby gene BTLA polymorphisms with the risk of renal cell carcinoma in the Polish population.
Urologic oncology - 1 Sept 2016
Partyka Anna, Tupikowski Krzysztof, Kolodziej Anna, Zdrojowy Romuald, Halon Agnieszka, Malkiewicz Bartosz, Dembowski Janusz, Frydecka Irena, Karabon Lidia
Abstract excerpt
OBJECTIVE: T cells play an important role in antitumor immunity, and molecules regulating T-cell activity could influence cancer susceptibility. The distinct role of coinhibitory receptors in immunosurveillance has been considered. B- and T-lymphocyte attenuator (BTLA) is one of these receptors, which negatively regulate immune responses. The aim of this study was to investigate the association between BTLA gene...
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