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Article

Outcome of T-cell acute lymphoblastic leukemia/lymphoma: Focus on near-ETP phenotype and differential impact of nelarabine.

American journal of hematology - 1 May 2021

Morita Kiyomi, Jain Nitin, Kantarjian Hagop, Takahashi Koichi, Fang Hong, Konopleva Marina, El Hussein Siba, Wang Feng, Short Nicholas J, Maiti Abhishek, Sasaki Koji, Garcia-Manero Guillermo, Konoplev Sergej, Ravandi Farhad, Khoury Joseph D, Jabbour Elias

Abstract excerpt

Early T-cell precursor acute lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) is characterized by a distinct immunophenotype (CD1a-negative, CD8-negative, CD5-negative or weak-positive <75%, myeloid/stem-cell markers positive) and poor clinical outcomes. Near-ETP ALL is transcriptionally similar to ETP-ALL but CD5 expression level is not low enough to meet the criteria of ETP immunophenotype. Outcomes of near-ETP...

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PMID: 33639000
DOI: 10.1002/ajh.26144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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