Recurrent membranous nephropathy after transplantation: donor antigen and HLA converge in defining risk.

doi:10.1016/j.kint.2020.10.044

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Article

Recurrent membranous nephropathy after transplantation: donor antigen and HLA converge in defining risk.

Kidney international - 1 Mar 2021

Robson Kate J, Kitching A Richard

Abstract excerpt

Membranous nephropathy, like many forms of glomerulonephritis, is an HLA-associated autoimmune disease that can recur in the transplanted kidney. In this issue of Kidney International, Berchtold and colleagues publish an intriguing and important paper on risk factors for recurrent post-transplant membranous nephropathy due to autoimmunity to PLA2R1. They found that the genetics of both the autoantigen and donor...

Topics

Alleles
Glomerulonephritis
Glomerulonephritis, Membranous
Humans
Kidney Transplantation
Receptors, Phospholipase A2
Recurrence
Tissue Donors

Source

Open in PubMed

Identifiers

PMID: 33637201
DOI: 10.1016/j.kint.2020.10.044

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