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Article

Deriving and understanding the risk of post-transplant recurrence of nephrotic syndrome in the light of current molecular and genetic advances.

Pediatric nephrology (Berlin, Germany) - 1 Nov 2018

Bierzynska Agnieszka, Saleem Moin A

Abstract excerpt

After renal transplantation, recurrence of the original disease is the second most common cause of graft loss, after rejection. The most dramatic manifestation of this phenomenon is in patients with nephrotic syndrome (NS). NS is a descriptive term describing a clinical picture centred on proteinuria arising from damage to the glomerular filtration barrier (GFB). There are many different drivers of that damage,...

Topics

Allografts
Biomarkers
Genetic Testing
Graft Survival
Humans
Kidney Failure, Chronic
Kidney Transplantation
Mutation
Nephrotic Syndrome
Podocytes
Recurrence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29022104
DOI: 10.1007/s00467-017-3793-2
PMCID: PMC6153493

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