Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responses

26 Feb 2021

Abstract excerpt

Previously, we reported that cellular transcription factor ZASC1 facilitates DNA-dependent/RNA-independent recruitment of HIV-1 TAT and the cellular elongation factor P-TEFb to the HIV-1 promoter and is a critical factor in regulating HIV-1 transcriptional elongation (PLoS Path e1003712). Here we report that cellular transcription factor ZBTB2 is a novel repressor of HIV-1 gene expression. ZBTB2 strongly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33635925
DOI: 10.1371/journal.ppat.1009364

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ZBTB2 represses HIV-1 transcription and is regulated by HIV-1 Vpr and cellular DNA damage responsesPMID 33635925Read ↗

Identification of Cellular Proteins Required for Replication of Human Immunodeficiency Virus Type 1Semantic proximity Read ↗

HIV-1 Transactivator of Transcription (Tat) Co-operates With AP-1 Factors to Enhance c-MYC TranscriptionSemantic proximity Read ↗

Genome-wide CRISPR knockout screen identifies ZNF304 as a silencer of HIV transcription that promotes viral latencySemantic proximity Read ↗

Chronic HIV‐1 Tat action induces HLA‐DR downregulation in B cells: A mechanism for lymphoma immune escape in people living with HIVSemantic proximity Read ↗

HIV Tat/P-TEFb Interaction: A Potential Target for Novel Anti-HIV TherapiesSemantic proximity Read ↗

The histone methyltransferase SETD2 regulates HIV expression and latency through a post-transcriptional mechanismSemantic proximity Read ↗

PHB2 inhibits WSSV replication by promoting the nuclear translocation of STATSemantic proximity Read ↗

FACT subunit SUPT16H associates with BRD4 and contributes to silencing of antiviral interferon signalingSemantic proximity Read ↗

Displacement of SATB1-bound histone deacetylase 1 corepressor by the human immunodeficiency virus type 1 transactivator induces expression of interleukin-2 and its receptor in T cells.Semantic proximity Read ↗

BET bromodomain inhibition as a novel strategy for reactivation of HIV-1Semantic proximity Read ↗

HTLV-1 bZIP Factor RNA and Protein Impart Distinct Functions on T-cell Proliferation and Survival.Semantic proximity Read ↗

A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.