Article
Association of mitochondrial DNA copy number with prevalent and incident type 2 diabetes in women: A population-based follow-up study.
Scientific reports - 25 Feb 2021
Memon Ashfaque A, Sundquist Jan, Hedelius Anna, Palmér Karolina, Wang Xiao, Sundquist Kristina
Abstract excerpt
Mitochondrial dysfunction is an important factor of the aging process and may play a key role in various diseases. Mitochondrial DNA copy number (mtDNA-CN) is an indirect measure of mitochondrial dysfunction and is associated with type 2 diabetes mellitus (T2DM); however, whether mtDNA-CN can predict the risk of developing T2DM is not well-known. We quantified absolute mtDNA-CN in both prevalent and incident T2DM...
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