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Association of mitochondrial DNA copy number with metabolic syndrome and type 2 diabetes in 14 176 individuals

16 Jan 2021

Abstract excerpt

Abstract Background Mitochondria play an important role in cellular metabolism, and their dysfunction is postulated to be involved in metabolic disturbances. Mitochondrial DNA is present in multiple copies per cell. The quantification of mitochondrial DNA copy number (mtDNA‐CN) might be used to assess mitochondrial dysfunction. Objectives We aimed to investigate the cross‐sectional association of mtDNA‐CN with...

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PMID: 33453124
DOI: 10.1111/joim.13242

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