Related Network and Differential Expression Analyses Identify Nuclear Genes and Pathways in the Hippocampus of Alzheimer Disease

Abstract excerpt

BACKGROUND Alzheimer disease (AD) is a typical progressive and destructive neurodegenerative disease that has been studied extensively. However, genetic features and molecular mechanisms underlying AD remain unclear. Here we used bioinformatics to investigate the candidate nuclear genes involved in the molecular mechanisms of AD. MATERIAL AND METHODS First, we used Gene Expression Omnibus (GEO) database to obtain...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to 14-3-3 protein interactions
• Share to Alzheimer's disease research and treatments
• Share to Bioinformatics and Genomic Networks