Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heightened frequency of innate immunity risk alleles in south Indian diabetics with urinary tract infections.

Human immunology - 1 Sept 2026

Balaji Priyanka, Emmanuel Bhaskar M, Gnanasambandan R, Sneha P, Samuel Senita, Bharath Govindasamy, Munirajan Arasambattu Kannan, Paul Solomon F D

Abstract excerpt

Urinary Tract Infections are an emerging public health concern among individuals with diabetes mellitus, particularly in South Asia where high disease burden, genetic diversity and increasing drug resistance contribute to the progressive increase in burden. While metabolic and clinical risk factors are well studied, the role of host innate immune genetic variations in shaping UTI susceptibility among diabetics...

Read the complete abstract on PubMed

Topics

Humans
Immunity, Innate
Urinary Tract Infections
Polymorphism, Single Nucleotide
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Case-Control Studies

Gene Frequency

India

Diabetes Mellitus, Type 2

Alleles

Toll-Like Receptor 4

Male

Middle Aged

Genotype

Mannose-Binding Lectin

Adult

Risk Factors

Source

Identifiers

PMID: 42456427
DOI: 10.1016/j.humimm.2026.111795

Genes

LTA
MBL2
TLR4

Variants

rs4986790

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heightened frequency of innate immunity risk alleles in south Indian diabetics with urinary tract infections.PMID 42456427Read ↗

Testing an association between TLR4 and CXCR1 gene polymorphisms with susceptibility to urinary tract infection in type 2 diabetes in north Indian population.Semantic proximity Read ↗

Diabetes Mellitus and Infection Susceptibility: An Immunometabolic InterfaceSemantic proximity Read ↗

Insights of Host Physiological Parameters and Gut Microbiome of Indian Type 2 Diabetic Patients Visualized via Metagenomics and Machine Learning ApproachesSemantic proximity Read ↗

Mannose-binding lectin and risk of infections in type 2 diabetes: A Danish cohort study.Semantic proximity Read ↗

Hospital-treated infectious diseases, genetic susceptibility and risk of type 2 diabetes: A population-based longitudinal study.Semantic proximity Read ↗

Genetic factors affect the susceptibility to bacterial infections in diabetes.Semantic proximity Read ↗

TLR1 polymorphism rs4833095 as a risk factor for IgA nephropathy in a Chinese Han population: A case-control study.Semantic proximity Read ↗

Association of CCL2, CCR5, ELMO1, and IL8 Polymorphism with Diabetic Nephropathy in Malaysian Type 2 Diabetic PatientsSemantic proximity Read ↗

Association of TLR2 gene Arg753Gln polymorphism with urinary tract infection in children.Semantic proximity Read ↗

SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.Semantic proximity Read ↗

Effect of IL-23 Receptor Gene Polymorphism (Rs1884444) on the Prevalence of Oral Fungal Infection in Patients with Type 2 Diabetes Mellitus: A Case-Control Study in Iraqi Patients.Semantic proximity Read ↗

Genetic Variants in NOS2 and CCL2 Modulate Risk of Post-COVID-19 Hyperglycemia via Immune-Metabolic Interactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.