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Article

Genetic factors affect the susceptibility to bacterial infections in diabetes.

Scientific reports - 4 May 2021

Simonsen Johan R, Käräjämäki Annemari, Antikainen Anni A, Toppila Iiro, Ahlqvist Emma, Prasad Rashmi, Mansour-Aly Dina, Harjutsalo Valma, Järvinen Asko, Tuomi Tiinamaija, Groop Leif, Forsblom Carol, Groop Per-Henrik, Sandholm Niina, Lehto Markku

Abstract excerpt

Diabetes increases the risk of bacterial infections. We investigated whether common genetic variants associate with infection susceptibility in Finnish diabetic individuals. We performed genome-wide association studies and pathway analysis for bacterial infection frequency in Finnish adult diabetic individuals (FinnDiane Study; N = 5092, Diabetes Registry Vaasa; N = 4247) using national register data on...

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Identifiers

PMID: 33947878
DOI: 10.1038/s41598-021-88273-w
PMCID: PMC8096814

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