Association between BRCA2 alterations and intraductal and cribriform histologies in prostate cancer.

doi:10.1016/j.ejca.2021.01.027

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Article

Association between BRCA2 alterations and intraductal and cribriform histologies in prostate cancer.

European journal of cancer (Oxford, England : 1990) - 1 Apr 2021

Lozano Rebeca, Salles Daniela C, Sandhu Shahneen, Aragón Isabel M, Thorne Heather, López-Campos Fernando, Rubio-Briones José, Gutierrez-Pecharroman Ana M, Maldonado Laneisha, di Domenico Tomas, Sanz Alejandro, Prieto Juan D, García Isabel, Pacheco María I, Garcés Teresa, Llacer Casilda, Romero-Laorden Nuria, Zambrana Francisco, López-Casas Pedro P, Lorente David, Mateo Joaquin, Pritchard Colin C, Antonarakis Emmanuel S, Olmos David, Lotan Tamara L, Castro Elena

Abstract excerpt

BACKGROUND: Intraductal (IDC) and cribriform (CRIB) histologies in prostate cancer have been associated with germline BRCA2 (gBRCA2) mutations in small retrospective series, leading to the recommendation of genetic testing for patients with IDC in the primary tumour. PATIENTS AND METHODS: To examine the association of gBRCA2 mutations and other tumour molecular features with IDC and/or cribriform (CRIB)...

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PMID: 33626496
DOI: 10.1016/j.ejca.2021.01.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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