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Genetic and Epigenetic Determinants of Aggressiveness in Cribriform Carcinoma of the Prostate

17 Oct 2018

Abstract excerpt

Abstract Among prostate cancers containing Gleason pattern 4, cribriform morphology is associated with unfavorable clinicopathologic factors, but its genetic features and association with long-term outcomes are incompletely understood. In this study, genetic, transcriptional, and epigenetic features of invasive cribriform carcinoma (ICC) tumors were compared with non-cribriform Gleason 4 (NC4) in The Cancer...

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PMID: 30333152
DOI: 10.1158/1541-7786.mcr-18-0440

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