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Article

Evidence for the loss and recovery of SLAMF9 during human evolution: implications on Dollo's law.

Immunogenetics - 1 Jun 2021

Murphy Maegan K, Moon Justin T, Skolaris Alexis T, Mikulin Joseph A, Wilson Timothy J

Abstract excerpt

Signaling lymphocyte activation molecule family member 9 (SLAMF9) is a cell surface protein of the CD2/SLAM family of leukocyte surface receptors. It is conserved throughout mammals and has roles in the initiation of inflammatory responses and regulation of plasmacytoid dendritic cell function. Through comparison of reference sequences encoding SLAMF9 in human, mouse, and primate sequences, we have determined...

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Identifiers

PMID: 33616677
DOI: 10.1007/s00251-021-01208-7
PMCID: PMC7898023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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