Article
Notch1 is an important mediator for enhancing of B-cell activation and antibody secretion by Notch ligand.
Immunology - 1 Dec 2014
Kang Jung-Ah, Kim Woo-Seok, Park Sung-Gyoo
Abstract excerpt
The roles of Notch1 and Notch2 in T-cell function have been well studied, but the functional roles of Notch in B cells have not been extensively investigated, except for Notch2 involvement in peripheral marginal zone B-cell differentiation. This study examined the roles of Notch1 in murine primar...
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