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Clinical and neuropathological variability in the rare IVS10 + 14 tau mutation.

Neurobiology of aging - 1 May 2021

Maxwell Selena P, Cash Meghan K, Rockwood Kenneth, Fisk John D, Darvesh Sultan

Abstract excerpt

Mutations in the microtubule-associated protein tau gene are known to cause progressive neurodegenerative disorders with variable clinical and neuropathological phenotypes, including the intronic 10 + 14 (IVS10 + 14) splice site mutation. Three families have been reported with the IVS10 + 14 microtubule-associated protein tau mutation. Here, we describe the clinical and neuropathological data from an additional...

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PMID: 33612310
DOI: 10.1016/j.neurobiolaging.2021.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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