Article
Atypical progressive supranuclear palsy with corticospinal tract degeneration.
Journal of neuropathology and experimental neurology - 1 Apr 2006
Josephs Keith A, Katsuse Omi, Beccano-Kelly Dayne A, Lin Wen-Lang, Uitti Ryan J, Fujino Yasuhiro, Boeve Bradley F, Hutton Michael L, Baker Matthew C, Dickson Dennis W
Abstract excerpt
Progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), sporadic multisystem tauopathy, and some forms of frontotemporal dementia with Parkinsonism linked to chromosome 17 are characterized by neuronal and glial lesions accumulating tau protein containing 4 conserved repeats in microtubule-binding domain (4R tau). Corticospinal tract degeneration is not a common feature of 4R tauopathies. Our...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.