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Article

Impact of cathepsin D activity and C224T polymorphism (rs17571) on chronic obstructive pulmonary disease: correlations with oxidative and inflammatory markers.

Clinical and experimental medicine - 1 Aug 2021

Bchir Sarra, Boumiza Soumaya, Ben Nasr Hela, Garrouch Abdelhamid, Kallel Imen, Tabka Zouhair, Chahed Karim

Abstract excerpt

BACKGROUND: Cathepsin D (CTSD) is an aspartyl proteinase that plays an important role in protein degradation, antigen processing and apoptosis. It has been associated with several pathologies such as cancer, Alzheimer's disease and inflammatory disorders. Its function in lung diseases remains, however, controversial. In the current study, we determined CTSD activity in serum of patients with chronic obstructive...

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Source

Identifiers

PMID: 33611777
DOI: 10.1007/s10238-021-00692-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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