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Article

Novel variants in DNAH9 lead to nonsyndromic severe asthenozoospermia.

Reproductive biology and endocrinology : RB&E - 20 Feb 2021

Tang Dongdong, Sha Yanwei, Gao Yang, Zhang Jingjing, Cheng Huiru, Zhang Junqiang, Ni Xiaoqing, Wang Chao, Xu Chuan, Geng Hao, He Xiaojin, Cao Yunxia

Abstract excerpt

BACKGROUND: Asthenozoospermia is one of the most common causes of male infertility, and its genetic etiology is poorly understood. DNAH9 is a core component of outer dynein arms in cilia and flagellum. It was reported that variants of DNAH9 (OMIM: 603330) might cause primary ciliary dyskinesia (PCD). However, variants in DNAH9 lead to nonsyndromic severe asthenozoospermia have yet to be reported. METHODS: Whole...

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Identifiers

PMID: 33610189
DOI: 10.1186/s12958-021-00709-0
PMCID: PMC7896388

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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