Article
Investigation of allele specific expression in various tissues of broiler chickens using the detection tool VADT.
Scientific reports - 17 Feb 2021
Tomlinson M Joseph, Polson Shawn W, Qiu Jing, Lake Juniper A, Lee William, Abasht Behnam
Abstract excerpt
Differential abundance of allelic transcripts in a diploid organism, commonly referred to as allele specific expression (ASE), is a biologically significant phenomenon and can be examined using single nucleotide polymorphisms (SNPs) from RNA-seq. Quantifying ASE aids in our ability to identify and understand cis-regulatory mechanisms that influence gene expression, and thereby assist in identifying causal...
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