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Plasma osteopontin as a biomarker of Alzheimer’s disease and vascular cognitive impairment

17 Feb 2021

Abstract excerpt

Cerebrovascular disease (CeVD) and neurodegenerative dementia such as Alzheimer's disease (AD) are frequently associated comorbidities in the elderly, sharing common risk factors and pathophysiological mechanisms including neuroinflammation. Osteopontin (OPN) is an inflammatory marker found upregulated in vascular diseases as well as in AD. However, its involvement in vascular dementia (VaD) and pre-dementia...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33597603
DOI: 10.1038/s41598-021-83601-6

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