Association of ApoE ε4 allele, homocysteine, and inflammatory factors (hs-CRP, IL-6, TNF-α) with cognitive dysfunction in Alzheimer's disease patients and development and validation of a predictive model.

Abstract excerpt

OBJECTIVE: This study focuses on the cognitive dysfunction in patients with Alzheimer's disease (AD), aims to in-depth analysis of the Apolipoprotein E (ApoE) gene polymorphism, homocysteine (Hcy) and the intrinsic relationship between the disease, and build accurate and effective prediction model. METHODS: A total of 193 AD patients were divided into a training set (n = 135) and a validation set (n = 58)...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Apolipoprotein E4
• Share to C-Reactive Protein