Article
Cell-to-cell variation in gene expression and the aging process.
GeroScience - 1 Feb 2021
Mendenhall Alexander R, Martin George M, Kaeberlein Matt, Anderson Rozalyn M
Abstract excerpt
There is tremendous variation in biological traits, and much of it is not accounted for by variation in DNA sequence, including human diseases and lifespan. Emerging evidence points to differences in the execution of the genetic program as a key source of variation, be it stochastic variation or programmed variation. Here we discuss variation in gene expression as an intrinsic property and how it could contribute...
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