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Article

EFEMP1 Overexpression Contributes to Neovascularization in Age-Related Macular Degeneration

15 Jan 2021

Abstract excerpt

Purpose: Age-related macular degeneration (AMD) is one of the leading causes of blindness, and choroidal neovascularization (CNV) in AMD can lead to serious visual impairment. Gene expression profiling of human ocular tissues have a great potential to reveal the pathophysiology of AMD. This study aimed to identify novel molecular biomarkers and gene expression signatures of AMD. Methods: We analyzed transcriptome...

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PMID: 33584252
DOI: 10.3389/fphar.2020.547436

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