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Article

Genetic analysis of GLT8D1 and ARPP21 in Australian familial and sporadic amyotrophic lateral sclerosis.

Neurobiology of aging - 1 May 2021

Chan Moi Fat Sandrine, McCann Emily P, Williams Kelly L, Henden Lyndal, Twine Natalie A, Bauer Denis C, Pamphlett Roger, Kiernan Matthew C, Rowe Dominic B, Nicholson Garth A, Fifita Jennifer A, Blair Ian P

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease caused by the progressive degeneration of motor neurons. Recently, genetic variants in GLT8D1 and ARPP21 were associated with ALS in a cohort of European descent. A synergistic relationship was proposed between ALS associated variants in GLT8D1 and ARPP21. We aimed to determine the prevalence of genetic variation in GLT8D1 and ARPP21 in an...

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PMID: 33581934
DOI: 10.1016/j.neurobiolaging.2021.01.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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