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Article

Mutation analysis of GLT8D1 and ARPP21 genes in amyotrophic lateral sclerosis patients from mainland China.

Neurobiology of aging - 1 Jan 2020

Li Wanzhen, Liu Zhen, Sun Weining, Yuan Yanchun, Hu Yiting, Ni Jie, Jiao Bin, Fang Liangjuan, Li Jinchen, Shen Lu, Tang Beisha, Wang Junling

Abstract excerpt

Variants in exon 4 of gene encoding GLT8D1 (glycosyltransferase 8 domain containing 1) gene have recently been suggested as a novel cause of amyotrophic lateral sclerosis (ALS). In addition, there is a synergism between GLT8D1 and ARPP21 (cAMP Regulated Phosphoprotein 21) variants for ALS. However, this observation has not been validated in other ALS cohorts. In this study, we analyzed the rare pathogenic...

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PMID: 31653410
DOI: 10.1016/j.neurobiolaging.2019.09.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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