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Article

New genetic causes for complex hereditary spastic paraplegia.

Journal of the neurological sciences - 15 Aug 2017

Souza Paulo Victor Sgobbi de, Bortholin Thiago, Dias Renan Braido, Chieia Marco Antônio Troccoli, Burlin Stênio, Naylor Fernando George Monteiro, Pinto Wladimir Bocca Vieira de Rezende, Oliveira Acary Souza Bulle

Abstract excerpt

INTRODUCTION: Hereditary Spastic Paraplegia (HSP) represents a complex and heterogeneous group of rare neurodegenerative disorders that share a common clinical feature of weakness and lower limb spasticity that can occur alone or in combination with a constellation of other neurological or systemic signs and symptoms. Although the core clinical feature of weakness and lower limb spasticity is virtually universal,...

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Source

Identifiers

PMID: 28716262
DOI: 10.1016/j.jns.2017.06.019

Genes

SPG11
SPG7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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