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Article

Associations Between Sleep Traits and Social Isolation: Observational and Bidirectional Mendelian Randomization Study.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jan 2024

Wang Jiao, Wang Ying, Jiang Chao Qiang, Zhu Tong, Zhu Feng, Jin Ya Li, Zhang Wei Sen, Xu Lin

Abstract excerpt

Social isolation has been found associated with multiple sleep traits in conventional observational studies. However, whether this association is causal and if so, its direction is uncertain. We analyzed the association between social isolation and multiple sleep traits in 30 430 participants from the Guangzhou Biobank Cohort Study. In bidirectional Mendelian randomization, we used 6, 17, and 11 single nucleotide...

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PMID: 37779488
DOI: 10.1093/gerona/glad233

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