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Article

MiRNA-mediated EMT and CSCs in cancer chemoresistance

12 Feb 2021

Abstract excerpt

Cancer stem cells (CSCs) are a small group of cancer cells, which contribute to tumorigenesis and cancer progression. Cancer cells undergoing epithelial-to-mesenchymal transition (EMT) acquire the chemoresistant ability, which is regarded as an important feature of CSCs. Thus, there emerges an opinion that the generation of CSCs is considered to be driven by EMT. In this complex process, microRNAs (miRNAs) are...

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PMID: 33579377
DOI: 10.1186/s40164-021-00206-5

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