RNAseq shows an all-pervasive day-night rhythm in the transcriptome of the pacemaker of the heart

Abstract excerpt

Abstract Physiological systems vary in a day-night manner anticipating increased demand at a particular time. Heart is no exception. Cardiac output is primarily determined by heart rate and unsurprisingly this varies in a day-night manner and is higher during the day in the human (anticipating increased day-time demand). Although this is attributed to a day-night rhythm in post-translational ion channel...

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