Article
The nuclear transporter importin-11 regulates the Wnt/β-catenin pathway and acts as a tumor promoter in glioma.
International journal of biological macromolecules - 15 Apr 2021
Ni Hongzao, Ji Daofei, Li Jing, Zhao Zongren, Zuo Jiandong
Abstract excerpt
Karyopherins mediate the macromolecular transport between the cytoplasm and the nucleus and participate in cancer progression. However, the role and mechanism of importin-11 (IPO11), a member of the karyopherin family, in glioma progression remain undefined. Effects of IPO11 on glioma progression were detected using CCK-8, colony formation assay, flow cytometry analysis, caspase-3 activity assay, and Transwell...
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